Sodium Azide → HCID 10405872, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 1 g of 5b (2.27 mmol) in 10 ml of CH3CN and 2 ml of water, NaN3 (0.592 g, 9.11 mmol) was added. The resulting suspension was stirred at 80° C. for 6 hours, then the solvent was removed under vacuum and the crude residue was diluted with water and extracted twice with ether. The organic layer was dried over anhydrous Na2SO4, and finally evaporated to obtain 0.790 g of crude product as a light yellow wax which was used without further purification with a yield of 98%;

Provenance & Evidence