Hydrochloric Acid → HCID 10357957, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 1.1 g of 9 (3.0 mmol) in 143 ml of HCl 2N was hydrogenated in H2 atmosphere overnight at 60 psi. After this time the residue was filtered and the acqueous phase was left under magnetic stirring for additional 48 hours at 40° C. Then the water was evaporated under vacuum and the residue was taken up twice with CH3CN (evaporating under vacuum every time) until a solid residue, insoluble in CH3CN, was obtained. The pale yellow wax was filtered and dried to give 0.300 g of final product with a yield of 32% which was used without further purification;

Provenance & Evidence