Ethanone, 1-(2,6,6-trimethyl-3-cyclohexen-1-yl)- → Ethanone, 1-(2,6,6-trimethyl-3-cyclohexen-1-yl)-

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Reaction Steps

In a 2,000-ml four-necked flask equipped with a thermometer, a condenser and a stirrer, placed were 2,6,6-trimethyl-3-cyclohexenyl methyl ketone (100 g) synthesized in Referential Example 1, dimethyl sulfoxide (1,500 ml) and potassium t-butoxide (35 g). Under stirring, they were reacted at 100° C. for 4 hours. The reaction mixture at this time was sampled and analyzed by gas chromatography, resulting in that the content of trans-2,6,6-trimethyl-3-cyclohexenyl methyl ketone (1a′) was 4%, while those of the 2,6,6-trimethyl-2-cyclohexenyl methyl ketone (1b) and the 2,6,6-trimethyl-1-cyclohexenyl methyl ketone (1c) thus produced were 64% and 32%, respectively.

Provenance & Evidence