2-Amino-4,5-dimethoxybenzonitrile → HCID 86610492, compound

HRID 2416196Notes

Reaction equation

HRID 2416196 reaction equation
[NH2:1][C:2]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[CH:6][C:3]=1[C:4]#[N:5].[N:14]1[CH:19]=[CH:18][C:17]([C:20]2([CH2:25][C:26](O)=[O:27])[NH:24][CH:23]=[CH:22][S:21]2)=[CH:16][CH:15]=1>>[C:4]([C:3]1[CH:6]=[C:7]([O:12][CH3:13])[C:8]([O:10][CH3:11])=[CH:9][C:2]=1[NH:1][C:26](=[O:27])[CH2:25][C:20]1([C:17]2[CH:18]=[CH:19][N:14]=[CH:15][CH:16]=2)[NH:24][CH:23]=[CH:22][S:21]1)#[N:5]

Participants

3

Reactant 2

HCID 7359672-Amino-4,5-dimethoxybenzonitrileHCID 86610488HCID 86610488, compound

Product 1

HCID 86610492HCID 86610492, compound

Procedure

This compound was prepared according to the method described in Example 1c by employing 2-amino-4,5-dimethoxybenzonitrile (Aldrich) and 2-(4-pyridyl)-thiazole acetic acid (Example 1, Step b) . Mp: 165-167° C. MS m/z: 381.1 (M+1). Calc'd for C19H16N4O3S: 380.09.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-8a51966541a348a9a852a45efac32d39
Source dataset
uspto-grants-2004_11
Patent number
US06822097B1

Reaction notes

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