2-Amino-4,5-dimethoxybenzonitrile → HCID 86610493, compound

HRID 2416197Notes

Reaction equation

HRID 2416197 reaction equation
[NH2:1][C:2]1[CH:9]=[C:8]([O:10][CH3:11])[C:7]([O:12][CH3:13])=[CH:6][C:3]=1[C:4]#[N:5].[N:14]1[CH:19]=[CH:18][CH:17]=[C:16]([C:20]2([CH2:25][C:26](O)=[O:27])[NH:24][CH:23]=[CH:22][S:21]2)[CH:15]=1>>[C:4]([C:3]1[CH:6]=[C:7]([O:12][CH3:13])[C:8]([O:10][CH3:11])=[CH:9][C:2]=1[NH:1][C:26](=[O:27])[CH2:25][C:20]1([C:16]2[CH:15]=[N:14][CH:19]=[CH:18][CH:17]=2)[NH:24][CH:23]=[CH:22][S:21]1)#[N:5]

Participants

3

Reactant 2

HCID 7359672-Amino-4,5-dimethoxybenzonitrileHCID 86610491HCID 86610491, compound

Product 1

HCID 86610493HCID 86610493, compound

Procedure

This compound was prepared according to the method described in Example 1c by employing 2-amino-4,5-dimethoxybenzonitrile (Aldrich) and 2-(3-pyridyl)-thiazole acetic acid (Example 2, Step b). Mp: 65-67° C. MS m/z: 381.1 (M+1). Calc'd for C19H16N4O3S: 380.09.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-fb5289d2269146e3b1d88da381425cb3
Source dataset
uspto-grants-2004_11
Patent number
US06822097B1

Reaction notes

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