N-Methylisopropylamine → HCID 10287379, compound

HRID 2416218Notes

Reaction equation

[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[S:8][CH:9]=[C:10]([C:12]3[C:13](=[O:24])[NH:14][C:15]4[C:20]([CH:21]=3)=[CH:19][CH:18]=[C:17]([CH:22]=O)[CH:16]=4)[N:11]=2)=[CH:3][CH:2]=1.[CH:25]([NH:28][CH3:29])([CH3:27])[CH3:26]>>[CH:25]([N:28]([CH2:22][C:17]1[CH:16]=[C:15]2[C:20]([CH:21]=[C:12]([C:10]3[N:11]=[C:7]([C:4]4[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=4)[S:8][CH:9]=3)[C:13](=[O:24])[NH:14]2)=[CH:19][CH:18]=1)[CH3:29])([CH3:27])[CH3:26]

Participants

Reactant 2

HCID 78485N-Methylisopropylamine

HCID 22638533HCID 22638533, compound

Product 1

HCID 10287379HCID 10287379, compound

Procedure

This compound was prepared according to the method described in example 8758 step (b) employing 3-(2-pyridin-4-yl-thiazol-4-yl)-1H-quinolin-2-one-7-carbaldehyde and N-isopropyl-N-methylamine to provide the desired compound as a yellow solid. MS m/z; 391.0 (M+1).

Workup

customThis compound was prepared

Sources & evidence

ORD record: ord-1d6b3d430acf4d14a49607f3120e3b83
Source dataset: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06822097B1

Reaction notes

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