Valinol → HCID 23527330, compound

HRID 2416235Notes

Reaction equation

HRID 2416235 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[S:8][CH:9]=[C:10]([C:12]3[C:13](=[O:24])[NH:14][C:15]4[C:20]([CH:21]=3)=[CH:19][CH:18]=[C:17]([CH:22]=O)[CH:16]=4)[N:11]=2)=[CH:3][CH:2]=1.[NH2:25][CH:26]([CH:29]([CH3:31])[CH3:30])[CH2:27][OH:28]>>[OH:28][CH2:27][CH:26]([NH:25][CH2:22][C:17]1[CH:16]=[C:15]2[C:20]([CH:21]=[C:12]([C:10]3[N:11]=[C:7]([C:4]4[CH:3]=[CH:2][N:1]=[CH:6][CH:5]=4)[S:8][CH:9]=3)[C:13](=[O:24])[NH:14]2)=[CH:19][CH:18]=1)[CH:29]([CH3:31])[CH3:30]

Participants

3

Reactant 2

HCID 79019ValinolHCID 22638533HCID 22638533, compound

Product 1

HCID 23527330HCID 23527330, compound

Procedure

This compound was prepared according to the method described in example 8768 employing 3-(2-pyridin-4-yl-thiazol-4-yl)-1H-quinolin-2-one-7-carbaldehyde and 2-amino-3-methyl-butan-1-ol to give a yellow solid. MS m/z: 421.3 (M+1).

Workup

  1. customThis compound was prepared
  2. customto give a yellow solid

Sources & evidence

ORD record
ord-b0f48939307e4a1985a1742371fbb6ae
Source dataset
uspto-grants-2004_11
Patent number
US06822097B1

Reaction notes

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