HuagongsheHuagongshe Chemistry Print Report · For research reference only
Naphthalen-2-yl-boron → 5-(3,5-Diethoxy-4-naphthalen-2-yl-benzyl)-pyrimidine-2,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Naphthalen-2-yl-boron | HCID 20596918 | — |
| Reactant | 5-(3,5-Diethoxy-4-iodo-benzyl)-pyrimidine-2,4-diamine | HCID 22636919 | — |
| Reactant | 5-(2,6-Diethoxy-biphenyl-4-ylmethyl)-pyrimidine-2,4-diamine | HCID 22636982 | — |
| Product | 5-(3,5-Diethoxy-4-naphthalen-2-yl-benzyl)-pyrimidine-2,4-diamine | HCID 22637021 | — |
Reaction Steps
Starting from 5-(3,5-diethoxy-4-iodo-benzyl)-pyrimidine-2,4-diamine (example 1) (414 mg; 1 mmol) and naphthalen-2-yl-boron acid (690 mg; 4 mmol), 327 mg (79%) 5-(2,6-diethoxy-biphenyl-4-ylmethyl)-pyrimidine-2,4-diamine [sic] are obtained as a colourless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06821980B1 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-ce2369c0cbab4dd8888ee4c1b18fc13b |
| Source note | uspto-grants-2004_11 |