HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 4253276, compound → Butane-2-sulphonic acid 4'-amino-4-(2,4-diamino-pyrimidin-5-ylmethyl)-6-ethoxy-3'-fluoro-biphenyl-2-yl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 4253276 | HCID 4253276 | — |
| Reactant | Butane-2-sulphonic acid 5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-ethoxy-2-iodo-phenyl ester | HCID 17937260 | — |
| Product | Butane-2-sulphonic acid 4'-amino-4-(2,4-diamino-pyrimidin-5-ylmethyl)-6-ethoxy-3'-fluoro-biphenyl-2-yl ester | HCID 17937366 | — |
Reaction Steps
Starting from 241 mg (0.84 mmol) N-(4-bromo-2-fluoro-phenyl)-2,2,2-trifluoro-acetamide and 214 mg (0.422 mmol) butane-2-sulphonic acid 5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-ethoxy-2-iodo-phenyl ester, 85 mg of the tide compound are obtained as a pale brown powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06821980B1 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-42c4ffe8803845b3a3f94047e214a1cf |
| Source note | uspto-grants-2004_11 |