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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2416330Generated: November 3, 2026

N-(4-bromo-2-methylphenyl)-2,2,2-trifluoroacetamide → HCID 86759563, compound

https://huagongshe.com/reaction/2416330

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(4-bromo-2-methylphenyl)-2,2,2-trifluoroacetamideHCID 789606—
ReactantHCID 17937271HCID 17937271—
ProductHCID 86759563HCID 8675956366%

Reaction Steps

Starting from 191 mg (0.68 mmol) N-(4-bromo-2-methyl-phenyl)-2,2,2-trifluoro-acetamide and 173 mg (0.34 mmol) 2-methyl-propane-1-sulphonic acid 5-(2,4-diamino-pyrimidin-5-ylmethyl)-3-ethoxy-2-iodo-phenyl ester, 109 mg of the title compound are obtained as a brown solid after chromatography and stirring in 5 ml ether.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06821980B1
Source datasetuspto-grants-2004_11
ORD IDord-25f85c69e7344363a972a6f8f66a2b5e
Source noteuspto-grants-2004_11