Chlorotrimethylsilane → HCID 58513592, compound

Participants

Reaction Steps

To a solution of tert-butyl 3-((1-(cyclopropylmethyl)-2-neopentyl-1H-benzo[d]imidazol-5-ylsulfonyl)methyl)azetidine-1-carboxylate (STEP E, 1.48 g, 3.11 mmol) in methanol (10 mL) was added chlorotrimethylsilane (1.35 g, 12.4 mmol). The resulting mixture was refluxed for 1 h. The reaction mixture was concentrated to give the title compound (1.26 g) as an amorphous.

Provenance & Evidence