2-Chloro-4-methoxypyrimidine → 4-(Pyridazin-3-yl)benzaldehyde

HRID 2416448Notes

Reaction equation

Cl[C:2]1[N:3]=[N:4][CH:5]=[CH:6][CH:7]=1.ClC1N=[C:13]([O:15]C)[CH:12]=[CH:11]N=1>>[N:4]1[CH:5]=[CH:6][CH:7]=[C:2]([C:6]2[CH:7]=[CH:2][C:12]([CH:13]=[O:15])=[CH:11][CH:5]=2)[N:3]=1

Participants

Reactant 2

HCID 5889352-Chloro-4-methoxypyrimidine

HCID 112749893-Chloropyridazine

Product 1

HCID 226309894-(Pyridazin-3-yl)benzaldehyde

Procedure

The title compound was prepared by a procedure analogous to Reference Example 13 by substituting 3-chloropyridazine (prepared as described in WO 9724124) for the 2-chloro-4-methoxypyrimidine of Reference Example 13. MS 185 (M+H)+.

Sources & evidence

ORD record: ord-2445ab0077844b82888c971fa1946e1a
Source dataset: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06825170B2

Reaction notes

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