4-(4-Pyridyl)benzaldehyde → (E)-3-[4-(4-Pyridinyl)phenyl]-2-propenal

HRID 2416466Notes

Reaction equation

HRID 2416466 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:14]=[CH:13][C:10]([CH:11]=O)=[CH:9][CH:8]=2)=[CH:3][CH:2]=1.N1(C2C=C[C:23]([CH:24]=[O:25])=CC=2)C=CC=N1>>[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[CH:14]=[CH:13][C:10](/[CH:11]=[CH:23]/[CH:24]=[O:25])=[CH:9][CH:8]=2)=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 6396734-(4-Pyridyl)benzaldehydeHCID 27764774-(1H-Pyrazol-1-yl)benzaldehyde

Product 1

HCID 22630986(E)-3-[4-(4-Pyridinyl)phenyl]-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-(4-pyridinyl)-benzaldehyde (prepared as described in WO 9828264) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 210 (M+H)+.

Sources & evidence

ORD record
ord-303c0f0d857647f98cf02569debbdcdf
Source dataset
uspto-grants-2004_11
Patent number
US06825170B2

Reaction notes

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