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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2416467Generated: November 1, 2026

4-(1H-Pyrazol-1-yl)benzaldehyde → (E)-3-[4-(5-Pyrimidinyl)phenyl]-2-propenal

https://huagongshe.com/reaction/2416467

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1H-Pyrazol-1-yl)benzaldehydeHCID 2776477—
Reactant5-(4-Formylphenyl)pyrimidineHCID 3861212—
Product(E)-3-[4-(5-Pyrimidinyl)phenyl]-2-propenalHCID 22631153—

Reaction Steps

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-(5-pyrimidinyl)-benzaldehyde (prepared as described in WO 9828264) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 211 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06825170B2
Source datasetuspto-grants-2004_11
ORD IDord-bcbbbab3b4d44448aec20985f73acab7
Source noteuspto-grants-2004_11