4-(1H-imidazol-1-yl)benzaldehyde → HCID 22631117, compound

HRID 2416470Notes

Reaction equation

HRID 2416470 reaction equation
[N:1]1([C:6]2[CH:13]=[CH:12][C:9]([CH:10]=O)=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1.N1(C2C=C[C:22]([CH:23]=[O:24])=CC=2)C=CC=N1>>[N:1]1([C:6]2[CH:13]=[CH:12][C:9](/[CH:10]=[CH:22]/[CH:23]=[O:24])=[CH:8][CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 7365304-(1H-imidazol-1-yl)benzaldehydeHCID 27764774-(1H-Pyrazol-1-yl)benzaldehyde

Product 1

HCID 22631117HCID 22631117, compound

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-(1H-imidazol-1-yl)-benzaldehyde (prepared as described in J. Med Chem. 1998, 41, 2390) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 199 (M+H)+.

Sources & evidence

ORD record
ord-81326ff3261d4e5e8b7aa7be56261d43
Source dataset
uspto-grants-2004_11
Patent number
US06825170B2

Reaction notes

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