4-(1H-Pyrazol-1-yl)benzaldehyde → (E)-3-[3-(2-Pyridinyl)phenyl]-2-propenal

HRID 2416472Notes

Reaction equation

HRID 2416472 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:8]=[C:9]([CH:12]=[CH:13][CH:14]=1)[CH:10]=O.N1(C2C=C[C:23]([CH:24]=[O:25])=CC=2)C=CC=N1>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[CH:8]=[C:9](/[CH:10]=[CH:23]/[CH:24]=[O:25])[CH:12]=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 37100393-(Pyridin-2-yl)benzaldehyde

Product 1

HCID 22630958(E)-3-[3-(2-Pyridinyl)phenyl]-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 3-(2-pyridinyl)benzaldehyde (prepared as described in Reference Example 11) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 210 (M+H)+.

Sources & evidence

ORD record
ord-fe448812dbda469fbf85e5f8a5ba9b05
Source dataset
uspto-grants-2004_11
Patent number
US06825170B2

Reaction notes

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