8-Quinolinecarboxaldehyde → HCID 11975945, compound
Reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2[CH:11]=O)[CH:4]=[CH:3][CH:2]=1.N1(C2C=C[C:21]([CH:22]=[O:23])=CC=2)C=CC=N1>>[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][C:9]=2/[CH:11]=[CH:21]/[CH:22]=[O:23])[CH:4]=[CH:3][CH:2]=1Participants
3
Procedure
The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 8-quinolinecarboxaldehyde (prepared as described in J. Am. Chem. Soc. 1997, 119, 8891) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 184 (M+H)+.
Sources & evidence
- ORD record
- ord-93ae15dea4f448e885e9e757bee8e303
- Source dataset
- uspto-grants-2004_11
- Patent number
- US06825170B2
Reaction notes
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