4-(1H-Pyrazol-1-yl)benzaldehyde → (2E)-3-[4-(3-pyrazinyl)phenyl]-2-propenal

HRID 2416489Notes

Reaction equation

HRID 2416489 reaction equation
[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7]1[CH:14]=[CH:13][C:10]([CH:11]=O)=[CH:9][CH:8]=1.N1(C2C=C[C:23]([CH:24]=[O:25])=CC=2)C=CC=N1>>[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7]1[CH:14]=[CH:13][C:10](/[CH:11]=[CH:23]/[CH:24]=[O:25])=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 38535194-(Pyrazin-2-yl)benzaldehyde

Product 1

HCID 22631067(2E)-3-[4-(3-pyrazinyl)phenyl]-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-pyrazinylbenzaldehyde (prepared as described in Reference Example 17) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 211 (M+H)+.

Sources & evidence

ORD record
ord-f44158f9b36d4622ac7e82f6e3bb52a6
Source dataset
uspto-grants-2004_11
Patent number
US06825170B2

Reaction notes

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