2-(4-Methylphenyl)-1,3-oxazole → 4-(1,2,4-Oxadiazol-5-yl)benzaldehyde

HRID 2416508Notes

Reaction equation

HRID 2416508 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][N:11]=[CH:10][N:9]=2)=[CH:4][CH:3]=1.CC1C=CC(C2[O:21]C=CN=2)=CC=1>>[O:12]1[C:8]([C:5]2[CH:4]=[CH:3][C:2]([CH:1]=[O:21])=[CH:7][CH:6]=2)=[N:9][CH:10]=[N:11]1

Participants

3

Reactant 2

HCID 123717532-(4-Methylphenyl)-1,3-oxazoleHCID 223397895-(4-Methylphenyl)-1,2,4-oxadiazole

Product 1

HCID 226309214-(1,2,4-Oxadiazol-5-yl)benzaldehyde

Procedure

The title compound is prepared by a procedure analogous to Step B of Reference Example 73 by substituting the 5-(4-methylphenyl)-1,2,4-oxadiazole from Step A above for the 2-(4-methylphenyl)oxazole of Step B of Reference Example 73. MS 175 (M+H)+.

Sources & evidence

ORD record
ord-af977cfab8d946beb4bd73de0a837516
Source dataset
uspto-grants-2004_11
Patent number
US06825170B2

Reaction notes

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