4-(Thiophen-2-yl)benzaldehyde → HCID 22630894, compound

HRID 2416515Notes

Reaction equation

HRID 2416515 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:13]=[CH:12][C:9]([CH:10]=O)=[CH:8][CH:7]=1.N1(C2C=C[C:22]([CH:23]=[O:24])=CC=2)C=CC=N1>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:13]=[CH:12][C:9](/[CH:10]=[CH:22]/[CH:23]=[O:24])=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 7364994-(Thiophen-2-yl)benzaldehydeHCID 27764774-(1H-Pyrazol-1-yl)benzaldehyde

Product 1

HCID 22630894HCID 22630894, compound

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-(2-thienyl)benzaldehyde (prepared as described in J. Med. Chem. 1998, 41, 2390) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 215 (M+H)+.

Sources & evidence

ORD record
ord-47cfc965f0f4443a80f9779c7af7deb6
Source dataset
uspto-grants-2004_11
Patent number
US06825170B2

Reaction notes

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