4-(1H-Pyrazol-1-yl)benzaldehyde → (2E)-3-[5-(2-Pyrazinyl)-2-thienyl]-2-propenal

HRID 2416520Notes

Reaction equation

HRID 2416520 reaction equation
[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7]1[S:11][C:10]([CH:12]=O)=[CH:9][CH:8]=1.N1(C2C=C[C:22]([CH:23]=[O:24])=CC=2)C=CC=N1>>[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7]1[S:11][C:10](/[CH:12]=[CH:22]/[CH:23]=[O:24])=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 534308925-(Pyrazin-2-yl)thiophene-2-carbaldehyde

Product 1

HCID 86590274(2E)-3-[5-(2-Pyrazinyl)-2-thienyl]-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 5-pyrazinyl-2-thiophenecarboxaldehyde (prepared as described in Reference Example 87) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 217 (M+H)+.

Sources & evidence

ORD record
ord-1cc022fc24234f02b082eb05b73661ff
Source dataset
uspto-grants-2004_11
Patent number
US06825170B2

Reaction notes

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