4-(1H-Pyrazol-1-yl)benzaldehyde → (2E)-3-(5-pyrazinyl-3-thienyl)-2-propenal

HRID 2416529Notes

Reaction equation

HRID 2416529 reaction equation
[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7]1[S:11][CH:10]=[C:9]([CH:12]=O)[CH:8]=1.N1(C2C=C[C:22]([CH:23]=[O:24])=CC=2)C=CC=N1>>[N:1]1[CH:6]=[CH:5][N:4]=[CH:3][C:2]=1[C:7]1[S:11][CH:10]=[C:9](/[CH:12]=[CH:22]/[CH:23]=[O:24])[CH:8]=1

Participants

3

Reactant 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 865902755-Pyrazinyl-3-thiophenecarboxaldehyde

Product 1

HCID 86590276(2E)-3-(5-pyrazinyl-3-thienyl)-2-propenal

Procedure

The title compound is prepared by a procedure analogous to Reference Example 30 by substituting 5-pyrazinyl-3-thiophenecarboxaldehyde (prepared as described in Reference Example 95) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 217 (M+H)+.

Sources & evidence

ORD record
ord-0b63625dc56245ee94768f51141b5d87
Source dataset
uspto-grants-2004_11
Patent number
US06825170B2

Reaction notes

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