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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2416554Generated: October 29, 2026

3-(2-Pyridinyl)-5-isoxazolemethanol → 2-(5-Formyl-isoxazol-3-yl)-pyridine

https://huagongshe.com/reaction/2416554

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2-Pyridinyl)-5-isoxazolemethanolHCID 686542—
Reactant3-[4-(2-Pyrimidinyl)phenyl]-2-propyn-1-olHCID 22631135—
Product2-(5-Formyl-isoxazol-3-yl)-pyridineHCID 22631228—

Reaction Steps

The title compound is prepared by a procedure analogous to Reference Example 300 by substituting 3-(2-pyridinyl)-5-isoxazolemethanol (prepared as described in J. Org. Chem. 2000, 65, 2225) for the 3-[4-(2-pyrimidinyl)phenyl]-2-propyn-1-ol of Reference Example 300. MS 175 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06825170B2
Source datasetuspto-grants-2004_11
ORD IDord-00a04aa184834277b84eacda9316cab4
Source noteuspto-grants-2004_11