Ethyl 3-(2-cyclopropyl-5-pyrimidinyl)-2-propenoate → HCID 75088804, compound

HRID 2416561Notes

Reaction equation

HRID 2416561 reaction equation
N1C=CCC(=NC=CC(OCC)=O)C=1.C1([C:18]2[N:23]=[CH:22][C:21]([CH:24]=[CH:25][C:26](OCC)=[O:27])=[CH:20][N:19]=2)CC1>>[N:19]1[CH:20]=[C:21]([CH:24]=[CH:25][CH:26]=[O:27])[CH:22]=[N:23][CH:18]=1

Participants

3

Reactant 2

HCID 54257216Ethyl 3-(2-cyclopropyl-5-pyrimidinyl)-2-propenoateHCID 69714005HCID 69714005, compound

Product 1

HCID 75088804HCID 75088804, compound

Procedure

The title compound was prepared by a procedure analogous to Reference Example 13 by substituting ethyl 3-(5-pyridiminyl)acrylate (prepared as described in WO0066566) for the ethyl 3-(2-cyclopropylpyrimidin-5-yl)acrylate of Reference Example 13. MS 135 (M+H)+.

Sources & evidence

ORD record
ord-b11356b11e3a40bfa6a5e31e37fc680c
Source dataset
uspto-grants-2004_11
Patent number
US06825172B2

Reaction notes

Loading…