HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2416582Generated: November 3, 2026
Triethyl phosphite → Methyl 4-(diethoxyphosphorylmethyl)benzoate
https://huagongshe.com/reaction/2416582
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | Methyl 4-(bromomethyl)benzoate | HCID 256687 | — |
| Product | Methyl 4-(diethoxyphosphorylmethyl)benzoate | HCID 10946061 | — |
Reaction Steps
6.64 g (40 mmol) of triethyl phosphite was added to 2.29 g (10 mmol) of methyl 4-(bromomethyl)benzoate, and they were stirred at 150° C. for 19 hours. The reaction solution was treated by the silica gel column chromatography to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06825181B1 |
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| Source dataset | uspto-grants-2004_11 |
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| ORD ID | ord-32768f993ebd4e5087b12d2141fb272f |
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| Source note | uspto-grants-2004_11 |
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