HCID 53826425, compound → HCID 22632182, compound

HRID 2416719Notes

Reaction equation

HRID 2416719 reaction equation
[N:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][C:2]=1[CH2:10][CH2:11][O:12][C:13]1[CH:29]=[CH:28][C:16]2[CH2:17][CH:18]([CH2:23][C:24]([O:26]C)=[O:25])[C:19](=[O:22])[NH:20][CH2:21][C:15]=2[CH:14]=1.N1C=CC=CC=1NCCCOC1C=CC2CC(CC(OCC)=O)C(=O)NCC=2C=1>>[N:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][C:2]=1[CH2:10][CH2:11][O:12][C:13]1[CH:29]=[CH:28][C:16]2[CH2:17][CH:18]([CH2:23][C:24]([OH:26])=[O:25])[C:19](=[O:22])[NH:20][CH2:21][C:15]=2[CH:14]=1

Participants

3

Reactant 2

HCID 53826425HCID 53826425, compoundHCID 54434818HCID 54434818, compound

Product 1

HCID 22632182HCID 22632182, compound

Procedure

According to the procedure of Example 1(c), except substituting methyl (±)-8-[2-(benzimidazol-2-yl)-1-ethoxy]-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate for the ethyl (±)-8-[3-(2-pyridylamino)-1-propyloxy]-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate, the title compound was prepared as a white powder: MS (ES) m/e 380.4 (M+H)+, 402.3 (M+Na)+.

Sources & evidence

ORD record
ord-64e6eab51ff748b1ae8f57bc70562ae6
Source dataset
uspto-grants-2004_11
Patent number
US06825188B2

Reaction notes

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