HCID 22631805, compound → HCID 22632248, compound

HRID 2416726Notes

Reaction equation

HRID 2416726 reaction equation
[N+:1]([C:4]1[CH:18]=[CH:17][C:7]([CH2:8][O:9][C:10]([NH:12][CH2:13][CH2:14][CH2:15][OH:16])=[O:11])=[CH:6][CH:5]=1)([O-:3])=[O:2].OCCCNC1C=CC=C[N+]=1[O-].O[C:32]1[CH:49]=[CH:48][C:35]2[CH2:36][CH:37]([CH2:43][C:44]([O:46][CH3:47])=[O:45])[C:38](=[O:42])[N:39]([CH3:41])[CH2:40][C:34]=2[CH:33]=1.OC1C=CC2CC(CC(OC)=O)C(=O)NCC=2C=1>>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([CH2:8][O:9][C:10]([NH:12][CH2:13][CH2:14][CH2:15][O:16][C:32]2[CH:49]=[CH:48][C:35]3[CH2:36][CH:37]([CH2:43][C:44]([O:46][CH3:47])=[O:45])[C:38](=[O:42])[N:39]([CH3:41])[CH2:40][C:34]=3[CH:33]=2)=[O:11])=[CH:17][CH:18]=1)([O-:3])=[O:2]

Participants

5

Reactant 4

HCID 22631805HCID 22631805, compoundHCID 53769834HCID 53769834, compoundHCID 54302492HCID 54302492, compoundHCID 178526251HCID 178526251, compound

Product 1

HCID 22632248HCID 22632248, compound

Procedure

According to the procedure of Example 1(a), except substituting 3-(4-nitrobenzyloxycarbonylamino)-1-propanol for the 2-[(3-hydroxy-1-propyl)amino]pyridine-N-oxide, and substituting methyl (±)-8-hydroxy-2-methyl-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate for the methyl (±)-8-hydroxy-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate, the tile compound was prepared as a colorless oil: MS (ES) m/e 500.3 (M+H)+.

Workup

  1. customthe tile compound was prepared as a colorless oil

Sources & evidence

ORD record
ord-68bc7b76b1ca46999df20ae1df1c22ca
Source dataset
uspto-grants-2004_11
Patent number
US06825188B2

Reaction notes

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