HCID 54434818, compound → HCID 22632286, compound

HRID 2416731Notes

Reaction equation

[CH2:1]([N:8]1[C:14](=[O:15])[CH:13]([CH2:16][C:17]([O:19]C)=[O:18])[CH2:12][C:11]2[CH:21]=[CH:22][C:23]([O:25][CH2:26][CH2:27][CH2:28][N:29]([C:37]3[CH:42]=[CH:41][CH:40]=[CH:39][N:38]=3)[C:30]([O:32][C:33]([CH3:36])([CH3:35])[CH3:34])=[O:31])=[CH:24][C:10]=2[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.N1C=CC=CC=1NCCCOC1C=CC2CC(CC(OCC)=O)C(=O)NCC=2C=1>>[CH2:1]([N:8]1[C:14](=[O:15])[CH:13]([CH2:16][C:17]([OH:19])=[O:18])[CH2:12][C:11]2[CH:21]=[CH:22][C:23]([O:25][CH2:26][CH2:27][CH2:28][N:29]([C:37]3[CH:42]=[CH:41][CH:40]=[CH:39][N:38]=3)[C:30]([O:32][C:33]([CH3:34])([CH3:35])[CH3:36])=[O:31])=[CH:24][C:10]=2[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 54434818HCID 54434818, compound

HCID 86591932HCID 86591932, compound

Product 1

HCID 22632286HCID 22632286, compound

Procedure

According to the procedure of Example 1(c), except substituting methyl (±)-2-benzyl-3-oxo-8-[3-[N-(pyridin-2-yl)-N-(tert-butoxycarbonyl)amino]-1-propyloxy]-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate for the ethyl (±)-8-[3-(2-pyridylamino)-1-propyloxy]-3-oxo-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetate, the title compound (0.044 g, quantitative) was prepared: MS (ES) m/e 560.3 (M+H)+.

Sources & evidence

ORD record: ord-7f775e85632b431aa141c7d3e028e45a
Source dataset: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06825188B2

Reaction notes

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