HuagongsheHuagongshe Chemistry Print Report · For research reference only
P-Anisidine → HCID 22632869, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | P-Anisidine | HCID 7732 | — |
| Reactant | Diisopropylamine | HCID 7912 | — |
| Reactant | 2,4,5-Trifluorobenzoic acid | HCID 521170 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | HCID 22632869 | HCID 22632869 | 120.5% |
Reaction Steps
Using General Method 1, the reaction of 2.5 M solution of n-BuLi in hexanes (26 mL, 64 mmol), diisopropylamine (8.7 mL, 62 mmol), 4-methoxy-aniline (2.6 g, 17 mmol), and 2,4,5-trifluorobenzoic acid (3.6 g, 20.7 mmol) provided 5.72 g of the crude title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06825199B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-4682dc0367ac450593c3a15b4c7e18d2 |
| Source note | uspto-grants-2004_11 |