HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 22632866, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | HCID 22632894 | HCID 22632894 | — |
| Product | HCID 22632866 | HCID 22632866 | 85.3% |
Reaction Steps
Using General Method 4, the reaction of N-methylpiperazine (0.12 mL, 1 mmol), triethylamine (0.14 mL, 1 mmol), and 1-(3-chloro-4-fluorophenyl)-3-benzyloxy-6,7-difluoro-1H-quinazoline-2,4-dione (Example D-1, 0.14 g, 0.32 mmol) provided 0.14 g of the title compound as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06825199B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-c10b8ddf65d34640b70ca2a707bf9ff4 |
| Source note | uspto-grants-2004_11 |