HCID 22632866, compound → HCID 22632959, compound

Participants

Reaction Steps

Using the General Method 6A, the reaction of 10% Pd/C (0.06 g) with 1-(3-chloro-4-fluorophenyl)-6-fluoro-3-benzyloxy-7-(4-methylpiperazin-1-yl)-1H-quinazoline-2,4-dione (Example R-1, 0.12 g, 0.23 mmol) afforded 0.085 g of the title compound as a solid, mp 197-199° C.

Provenance & Evidence