4-Bromo-3,5-dimethyl-1,2-oxazole → 2-Chloro-4-(3,5-dimethyl-isoxazol-4-yl)-pyridine

Participants

Role	Name	HCID	Charge
Reactant	4-Bromo-3,5-dimethyl-1,2-oxazole	HCID 318421	—
Reactant	2-Chloro-4-[1-(tetrahydro-pyran-2-yl)-1H-pyrazol-4-yl]-pyridine	HCID 59534355	—
Product	2-Chloro-4-(3,5-dimethyl-isoxazol-4-yl)-pyridine	HCID 59534449	—

Reaction Steps

The title compound was prepared from 4-bromo-3,5-dimethylisoxazole generally according to the synthetic procedure described for 2-Chloro-4-[1-(tetrahydro-pyran-2-yl)-1H-pyrazol-4-yl]-pyridine. UPLC (Rt)=0.81 min (method N)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08653075B2
Source dataset	uspto-grants-2014_02
ORD ID	ord-0992ca5b14c9467bbe6571b646fc8f1a
Source note	uspto-grants-2014_02