HCID 131723243, compound → HCID 58726315, compound

Participants

Reaction Steps

Z-L-Phe-D-Pro-OtBu (1.403 g, 3.1 mmol) was catalytically hydrogenated with Pd-C in acetic acid to remove the Z-group. After the reaction was continued for 10 hours, Pd-C was filtered off and acetic acid was concentrated. The residue was neutralized with 4% NaHCO3 and extracted into ethyl acetate. The extract was dried over Na2CO3 and concentrated to yield 0.853 g (86%) of the titled compound.

Provenance & Evidence