1-Bromo-2-butyne → HCID 11152913, compound

HRID 2417267Notes

Reaction equation

HRID 2417267 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH:9]([C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)[C:10]([O:12][CH2:13][CH3:14])=[O:11])=[CH:4][CH:3]=1.Br[CH2:24][C:25]#[C:26][CH3:27]>>[CH2:13]([O:12][C:10](=[O:11])[CH:9]([S:8][C:5]1[CH:6]=[CH:7][C:2]([O:1][CH2:24][C:25]#[C:26][CH3:27])=[CH:3][CH:4]=1)[C:15]1[CH:16]=[CH:17][C:18]([O:21][CH3:22])=[CH:19][CH:20]=1)[CH3:14]

Participants

3

Reactant 2

HCID 27568621-Bromo-2-butyneHCID 11290118HCID 11290118, compound

Product 1

HCID 11152913HCID 11152913, compoundYield 96%

Procedure

Ethyl{[4-(2-butynyloxy)phenyl]sulfanyl}(4-methoxyphenyl)acetate was prepared according to the general method as outlined in example 1 (step 1), starting from ethyl [(4-hydroxyphenyl)sulfanyl](4-methoxyphenyl)acetate (15.82 g, 49.7 mmol) and 4-bromo-2-butyne (4.79 ml, 54.7 mmol); 17.66 g yellow oil. Yield 96%; MS(EI): 370.1 (M+H)+

Sources & evidence

ORD record
ord-28dc89dfe9a943c3b94674e3d5b0d5c7
Source dataset
uspto-grants-2004_11
Patent number
US06825354B2

Reaction notes

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