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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2417268Generated: October 27, 2026

Ethyl 2-bromo-2-(4-chlorophenyl)acetate → Ethyl(4-chlorophenyl)[(4-hydroxyphenyl)sulfanyl]acetate

https://huagongshe.com/reaction/2417268

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-bromo-2-(4-chlorophenyl)acetateHCID 228840—
Reactant4-MercaptophenolHCID 240147—
ProductEthyl(4-chlorophenyl)[(4-hydroxyphenyl)sulfanyl]acetateHCID 9143209797%

Reaction Steps

Ethyl(4-chlorophenyl)[(4-hydroxyphenyl)sulfanyl]acetate was prepared according to the general method as outlined in example 1 (step 1), starting from ethyl bromo(4-chlorophenyl)acetate (16.5 g, 59.6 mmol) and 4-mercaptophenol (7.5 g, 59.6 mmol); 18.8 g white solid. mp: 63° C.; Yield 97%; MS: 321.3 (M−H)−

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06825354B2
Source datasetuspto-grants-2004_11
ORD IDord-66f87649ff7a4385a98b78b68f10c182
Source noteuspto-grants-2004_11