4-Mercaptophenol → HCID 86757739, compound

HRID 2417276Notes

Reaction equation

Br[CH:2]([C:8]1[CH:13]=[CH:12][C:11]([C:14]2[S:15][CH:16]=[CH:17][CH:18]=2)=[CH:10][CH:9]=1)[C:3]([O:5][CH2:6][CH3:7])=[O:4].[SH:19][C:20]1[CH:25]=[CH:24][C:23]([OH:26])=[CH:22][CH:21]=1>>[CH2:6]([O:5][C:3](=[O:4])[CH:2]([S:19][C:20]1[CH:25]=[CH:24][C:23]([OH:26])=[CH:22][CH:21]=1)[C:8]1[CH:13]=[CH:12][C:11]([C:14]2[S:15][CH:16]=[CH:17][CH:18]=2)=[CH:10][CH:9]=1)[CH3:7]

Participants

Reactant 2

HCID 2401474-Mercaptophenol

HCID 88041844HCID 88041844, compound

Product 1

HCID 86757739HCID 86757739, compoundYield 73%

Procedure

Ethyl[(4-hydroxyphenyl)sulfanyl][4-(2-thienyl)phenyl]acetate was prepared according to the general method as outlined in example 1 (step 1), starting from ethyl bromo[4-(2-thienyl)phenyl]acetate (2 g, 6.15 mmol) and 4-mercaptophenol (0.82 g, 6.5 mmol); 1.68 g white solid. mp: 103° C.; Yield 73%; MS: 369.1 (M−H)−

Sources & evidence

ORD record: ord-2b965f1bfb6145e2938069c31fa388e1
Source dataset: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06825354B2

Reaction notes

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