HCID 10133815, compound → HCID 10200222, compound

HRID 2417283Notes

Reaction equation

HRID 2417283 reaction equation
[CH2:1]([O:5][C:6]1[CH:11]=[CH:10][C:9]([S:12][CH:13]([C:18]2[CH:23]=[CH:22][C:21]([O:24][CH2:25][CH3:26])=[CH:20][CH:19]=2)[C:14]([NH:16][OH:17])=[O:15])=[CH:8][CH:7]=1)[C:2]#[C:3][CH3:4].C([O:29]C1C=CC(CC(N)=O)=CC=1)C>>[CH2:1]([O:5][C:6]1[CH:7]=[CH:8][C:9]([S:12]([CH:13]([C:18]2[CH:23]=[CH:22][C:21]([O:24][CH2:25][CH3:26])=[CH:20][CH:19]=2)[C:14]([NH:16][OH:17])=[O:15])=[O:29])=[CH:10][CH:11]=1)[C:2]#[C:3][CH3:4]

Participants

3

Reactant 2

HCID 10133815HCID 10133815, compoundHCID 152084284-Ethoxybenzeneacetamide

Product 1

HCID 10200222HCID 10200222, compoundYield 73%

Procedure

Starting from 2-{[4-(2-butynyloxy)phenyl]sulfanyl}-N-hydroxy-2-(4-ethoxyphenyl)acetamide (808 mg, 2.27 mmol) and following the procedure as outlined in Example 7, 640 mg of 2-{[4-(2-Butynyloxy)phenyl]sulfinyl}-N-hydroxy-2-(4-ethoxyphenyl acetamide was isolated as a brown powder. Yield: 73%; MS: 388.2 (M+H)+. Mp: 192-193.

Workup

  1. customwas isolated as a brown powder

Sources & evidence

ORD record
ord-86c6f6eafcf74556b4b1de29ab12c1b0
Source dataset
uspto-grants-2004_11
Patent number
US06825354B2

Reaction notes

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