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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 241729Generated: October 26, 2026

3-Methylsulphanyl-5-(2-oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-one → 5-(2-Oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-one

https://huagongshe.com/reaction/241729

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methylsulphanyl-5-(2-oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-oneHCID 66636411—
CatalystZincHCID 23994—
SolventAcetic AcidHCID 176—
Product5-(2-Oxo-oxazolidin-3-ylmethyl)-1,3-dihydro-indol-2-oneHCID 66636156—

Reaction Steps

To a solution of the compound obtained in Step C in glacial acetic acid (320 ml) there is added powdered zinc (1 mol). The reaction mixture is stirred overnight at ambient temperature and is then filtered. The filtrate is concentrated, and then 100 ml of water are added. The solid formed is filtered off and then recrystallised from ethanol to yield the title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08653073B2
Source datasetuspto-grants-2014_02
ORD IDord-3bef86fba7a146f5890b03e4b656655a
Source noteuspto-grants-2014_02