HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Hydroxyphthalimide → HCID 22633846, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Hydroxyphthalimide | HCID 10665 | — |
| Reactant | 5-Hexyn-1-ol | HCID 70234 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22633846 | HCID 22633846 | — |
Reaction Steps
To 5-Hexyn-1-ol is added N-hydroxyphthalimide (1.1 equivalent) in dry THF. To this mixture is added diethylazo-dicarboxylate (DEAD) dropwise with stirring at ambient temperature for 18 hours. Evaporation of the reaction mixture followed by silica column purification yielded the 1-phthalimidooxy-hex-5-yne.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06825331B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-eef326f7f4904a838fdbdb8defacd4ea |
| Source note | uspto-grants-2004_11 |