HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-1H-pyrrole-2-carbaldehyde → 4-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-pyrrolecarboxaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-1H-pyrrole-2-carbaldehyde | HCID 599627 | — |
| Reactant | (5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)boronic acid | HCID 10353857 | — |
| Product | 4-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-2-pyrrolecarboxaldehyde | HCID 22634685 | 21.7% |
Reaction Steps
In a similar manner to Example 3(b), by reaction of 5.9 g (25.6 mmol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylboronic acid with 3.7 g (21.3 mmol) of 4-bromo-2-pyrrolecarboxaldehyde, 1.3 g (21.6%) of the expected product are obtained, with a melting point of 211-2° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06825360B1 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-7d08605fb68a4c4d8be09bc677204d99 |
| Source note | uspto-grants-2004_11 |