Boronic Acid → HCID 22634656, compound

HRID 2417335Notes

Reaction equation

HRID 2417335 reaction equation
Br[C:2]1[C:3]([O:16][CH2:17][O:18][CH3:19])=[CH:4][C:5]2[C:6]([CH3:15])([CH3:14])[CH2:7][CH2:8][C:9]([CH3:13])([CH3:12])[C:10]=2[CH:11]=1.[BH:20]([OH:22])[OH:21]>>[CH3:19][O:18][CH2:17][O:16][C:3]1[CH:2]=[CH:11][C:10]2[C:9]([CH3:13])([CH3:12])[CH2:8][CH2:7][C:6]([CH3:15])([CH3:14])[C:5]=2[C:4]=1[B:20]([OH:22])[OH:21]

Participants

3

Reactant 2

HCID 61668Boronic AcidHCID 108536296-Bromo-7-(methoxymethoxy)-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene

Product 1

HCID 22634656HCID 22634656, compound

Procedure

In a similar manner to Example 3(a), starting with 8 g (24.4 mmol) of 3-bromo-2-methoxymethoxy-5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalene, 5.5 g (77%) of the expected boronic acid are obtained, with a melting point of 133-4° C.

Workup

  1. customare obtained, with a melting point of 133-4° C.

Sources & evidence

ORD record
ord-d14a202508ee4036a058d646bfeeba69
Source dataset
uspto-grants-2004_11
Patent number
US06825360B1

Reaction notes

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