Boronic Acid → HCID 22634691, compound

HRID 2417340Notes

Reaction equation

HRID 2417340 reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[CH3:12])[S:8][CH2:7][CH2:6][C:5]2([CH3:14])[CH3:13].[BH:15]([OH:17])[OH:16]>>[CH3:13][C:5]1([CH3:14])[C:4]2[C:9](=[CH:10][C:11]([CH3:12])=[CH:2][CH:3]=2)[S:8][CH:7]([B:15]([OH:17])[OH:16])[CH2:6]1

Participants

3

Reactant 2

HCID 61668Boronic AcidHCID 156611176-Bromo-4,4,7-trimethylthiochroman

Product 1

HCID 22634691HCID 22634691, compound

Procedure

In a similar manner to Example 3(a), starting with 5.8 g (21.4 mmol) of 6-bromo-4,4,7-trimethylthiochroman, 3.88 g (76%) of the expected boronic acid are obtained, with a melting point of 252-3° C.

Workup

  1. customare obtained, with a melting point of 252-3° C.

Sources & evidence

ORD record
ord-0410ee24c7014216bbdb930da6e99cb1
Source dataset
uspto-grants-2004_11
Patent number
US06825360B1

Reaction notes

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