HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (3-Chloro-benzyl)-(2-piperazin-1-yl-pyrimidin-4-yl)-amine, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 4-[4-(3-Chloro-benzylamino)-pyrimidin-2-yl]-piperazine-1-carboxylic Acid Tert-Butyl Ester | HCID 69596315 | — |
| Product | (3-Chloro-benzyl)-(2-piperazin-1-yl-pyrimidin-4-yl)-amine, hydrochloride | HCID 131724681 | — |
Reaction Steps
The title compound (4-A) was prepared from 4-[4-(3-chloro-benzylamino)-pyrimidin-2-yl]-piperazine-1-carboxylic acid tert-butyl ester (I-4a) and TFA according to a procedure analogous to that described in Example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06825198B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-5a5e08db92ee44cd8db14070a9bd00ff |
| Source note | uspto-grants-2004_11 |