3-Carboxyphenylboronic acid → HCID 22633235, compound

HRID 2417387Notes

Reaction equation

HRID 2417387 reaction equation
C([O:4][C:5]1[C:12]([O:13][CH3:14])=[CH:11][C:8]([CH:9]=[O:10])=[C:7](Br)[C:6]=1[O:16][CH3:17])(=O)C.[C:18]([C:21]1[CH:22]=[C:23](B(O)O)[CH:24]=[CH:25][CH:26]=1)([OH:20])=[O:19]>>[CH:9]([C:8]1[C:7]([C:25]2[CH:24]=[CH:23][CH:22]=[C:21]([C:18]([OH:20])=[O:19])[CH:26]=2)=[C:6]([O:16][CH3:17])[C:5]([OH:4])=[C:12]([O:13][CH3:14])[CH:11]=1)=[O:10]

Participants

3

Reactant 2

HCID 27339573-Carboxyphenylboronic acidHCID 22633147HCID 22633147, compound

Product 1

HCID 22633235HCID 22633235, compound

Procedure

6′-Formyl-3′-hydroxy-2′,4′-dimethoxy-biphenyl-3-carboxylic acid was prepared from 4-acetoxy-2-bromo-3,5-dimethoxybenzaldehyde (Example 162, step a) and 3-carboxyphenyl boronic acid using the protocol described in Example 145, step a. Mass Spectrum 288 (M+1).

Sources & evidence

ORD record
ord-e57f85634e5b4cc3a056130b1d806bbf
Source dataset
uspto-grants-2004_11
Patent number
US06825208B2

Reaction notes

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