HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2417538Generated: November 1, 2026
N-bromobutanimide → 6-(Bromomethyl)pyridine-3-carbonitrile
https://huagongshe.com/reaction/2417538
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 6-Methylpyridine-3-carbonitrile | HCID 281995 | — |
| Reactant | Perbenzoic acid | HCID 523077 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 6-(Bromomethyl)pyridine-3-carbonitrile | HCID 21927776 | — |
Reaction Steps
0.3 g (2.5 mmol) of 5-cyano-2-methylpyridine was dissolved in 15 ml of benzene. 10 mg of perbenzoic acid and 0.49 g (2.8 mmol) of N-bromosuccinimide were added to the obtained solution, and they were stirred at 75° C. for 2 days. The solvent was evaporated and the crude product was purified by the silica gel column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06825191B2 |
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| Source dataset | uspto-grants-2004_11 |
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| ORD ID | ord-3c93eab1a1d2460f9defb51753fa1bc1 |
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| Source note | uspto-grants-2004_11 |
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