HCID 20278283, compound → HCID 13324054, compound

HRID 2417578Notes

Reaction equation

HRID 2417578 reaction equation
CC1(C)[NH:6][CH:5]([P:7](=[O:10])([OH:9])[OH:8])[C:4]([CH3:12])([CH3:11])[S:3]1>O>[NH2:6][CH:5]([P:7](=[O:8])([OH:10])[OH:9])[C:4]([SH:3])([CH3:12])[CH3:11]

Participants

3

Reactant 1

HCID 20278283HCID 20278283, compound

Product 1

HCID 13324054HCID 13324054, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
0 °C

Procedure

2.0 g of DL-(2,2,5,5-tetramethyl-4-thiazolidinyl)phosphonic acid (prepared as described in Example 1) were dissolved in boiling water and the solution was concentrated by boiling off excess water until a crystalline solid began to separate. The mixture was cooled to 0° C. and the white crystals were collected. There was obtained 0.6 g of DL-(1-amino-2-mercapto-2-methylpropyl)phosphonic acid of melting point 242°-244° C. (decomposition).

Workup

  1. concentrationthe solution was concentrated
  2. customto separate
  3. customthe white crystals were collected

Sources & evidence

ORD record
ord-e7857b3cfbab407890c0a86b6b3be0be
Source dataset
uspto-grants-1984_09
Patent number
US04469686

Reaction notes

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