HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxy-2,4,6-cycloheptatrien-1-one → 2-(3-Methyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxy-2,4,6-cycloheptatrien-1-one | HCID 16546 | — |
| Reactant | 2-Methylpiperazine | HCID 66057 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(3-Methyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one | HCID 15592161 | 70.6% |
Reaction Steps
A solution of 2-methoxy-2,4,6-cycloheptatrien-1-one (6.8 g) and 2-methylpiperazine (5 g) in methanol was refluxed for 16 hr and evaporated. The residue (11 g) was chromatographed on silica gel (250 g) using methanol and the eluate was evaporated to give 7.2 g of 2-(3-methyl-1-piperazinyl)-2,4,6-cycloheptatrien-1-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04469695 |
| Source dataset | uspto-grants-1984_09 |
| ORD ID | ord-84f7ed64c42844faa02e74a38290a30a |
| Source note | uspto-grants-1984_09 |