Sodium Hydroxide → HCID 20446512, compound

HRID 2417754Notes

Reaction equation

HRID 2417754 reaction equation
O.Br.[CH3:3][C:4]1[CH:13]=[C:12]([NH2:14])[C:11]([N+:15]([O-:17])=[O:16])=[CH:10][C:5]=1[NH:6][CH2:7][CH2:8][NH2:9].[OH-].[Na+]>O>[CH3:3][C:4]1[CH:13]=[C:12]([NH2:14])[C:11]([N+:15]([O-:17])=[O:16])=[CH:10][C:5]=1[NH:6][CH2:7][CH2:8][NH2:9]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 20446511HCID 20446511, compound

Product 1

HCID 20446512HCID 20446512, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The hydrobromide thus obtained is dissolved in water. After the solution has been rendered alkaline with the aid of a 2N sodium hydroxide solution, the 2-methyl-4-amino-5-nitro-N-(β-aminoethyl)-aniline is filtered off. After washing with water, drying and recrystallisation from ethyl acetate, the product melts at 115° C.

Workup

  1. filtrationthe 2-methyl-4-amino-5-nitro-N-(β-aminoethyl)-aniline is filtered off
  2. washAfter washing with water
  3. customdrying
  4. customrecrystallisation from ethyl acetate

Sources & evidence

ORD record
ord-93087f51c3d64787900243bbb55a0b3c
Source dataset
uspto-grants-1984_09
Patent number
US04470826

Reaction notes

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