Sodium Hydroxide → HCID 22827555, compound

HRID 2417779Notes

Reaction equation

[C:1]([CH:4]([NH:13][C@H:14]([C:16]([N:18]1[C@H:26]([C:27]([OH:29])=[O:28])[CH2:25][C:20]2([S:24][CH2:23][CH2:22][S:21]2)[CH2:19]1)=[O:17])C)[CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([OH:3])=[O:2].[OH-].[Na+]>>[C:1]([CH:4]([NH:13][CH2:14][C:16]([N:18]1[C@H:26]([C:27]([OH:29])=[O:28])[CH2:25][C:20]2([S:24][CH2:23][CH2:22][S:21]2)[CH2:19]1)=[O:17])[CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)([OH:3])=[O:2]

Participants

Reactant 2

HCID 14798Sodium Hydroxide

HCID 86739619HCID 86739619, compound

Product 1

HCID 22827555HCID 22827555, compound

Procedure

As described in Example 2, hydrolyze 7-[N-(1-carboethoxy-3-phenylpropyl)glycyl]-1,4-dithia-7-azaspiro[4.4]nonane-8(S)-carboxylic acid (prepared as described in Example 2) with sodium hydroxide to give the title compound.

Sources & evidence

ORD record: ord-1718b213f47d4510827f4054efc15685
Source dataset: uspto-grants-1984_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04470972

Reaction notes

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