HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 20269005, compound → 3,4,5,6-Tetrahydro-1-benzazocin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 20269005 | HCID 20269005 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3,4,5,6-Tetrahydro-1-benzazocin-2(1H)-one | HCID 12433953 | — |
Reaction Steps
A solution of 6-acetoxy-3,4,5,6-tetrahydro-1-benzazocin-2(1H)-one (7.4 g) in ethanol (250 ml) is hydrogenated at 45 psi at 70° C. using 10% palladium on charcoal (1.5 g) as catalyst. The catalyst is filtered off and the solvent removed under reduced pressure. The residue is recrystallized from methanol/ethyl acetate to give 3,4,5,6-tetrahydro-1-benzazocin-2(1H)-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04470988 |
| Source dataset | uspto-grants-1984_09 |
| ORD ID | ord-1c0183dbf2c84d58b0d2ea8fca186e74 |
| Source note | uspto-grants-1984_09 |